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Dr 

Osunsanmi, Foluso Oluwagbemiga

Faculty: Faculty of Science, Agriculture and Engineering
Department: Agriculture
Research Interest(s): Clinical biochemistry, Bio-informatics, Food biochemistry, Plants biochemistry, Medicinal chemistry, Ethno-pharmacology, Natural product synthetic chemistry, Functional food, Metabolic diseases, Nutritional biochemistry, Microbiology, Biotechnology, Proteomics.
Biography: Dr. Foluso O Osunsanmi is currently a Research Fellow at the Department of Biochemistry and Microbiology, University of Zululand, South Africa. He is a biochemist with twenty years’ work experiences both in academic and industrial sectors. He had supervised both undergraduate and postgraduate students. He also has notable numbers of publications in reputable journals and had presented both in local and international conferences. He regularly performs peer reviews for over twenty-two different reputable journals. He is an Academic Editor of many International journals. He is also member of South Africa Association Council for Natural Scientific Professions, South Africa Association of Clinical Biochemistry, South Africa Association of Botanist and National Association of Safety professional.
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20221
Author: Osunsanmi, Foluso Oluwagbemiga × Subject: ACE ×
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    PublicationJournal Article
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    Effects of methanolic crude extracts Inula glomerata and Salacia kraussii on erectile dysfunction
    2022
     | Bioline Internationa...
    Inula glomerata Oliv. & Hiern and Salacia kraussii (Harv.) Harv are medicinal plants used by traditional healers in remote areas of Mbazwana, Northern KwaZulu-Natal, South Africa for ameliorating male sexual disorders including erectile dysfunction (ED), low sperm count and early ejaculation. The study aimed at determining the ameliorative effect of the methanolic crude extracts of Inula glomerata (I. glomerata) and Salacia kraussii (S. kraussii) on butanol-induced erectile dysfunction in Sprague Dawley rats. The crude extract was prepared by maceration using methanol. Animal study was conducted whereby thirty-five male Sprague Dawley rats were divided into seven experimental groups: normal group, n-but (10 mg/kg), n-but+ Ig (50 and 250 mg/kg), n-but+ Sk (50 and 250 mg/kg) and n-but+ Cialis (5mg/kg). The experiment lasted for 28 days, after which various biochemical assays (acetylcholinesterase, ACE, arginase, testosterone, and uric acid) was done. The cytotoxicity of the crude extracts was also determined. The results revealed that n-butanol induced erectile dysfunction in the rats by decreasing mounting frequency, testosterone and nitric oxide level and simultaneously elevated the activities of arginase and acetylcholinesterase. The plants however, inhibited arginase and acetylcholinesterase when compared to the untreated. Furthermore, the plants’ extracts were able to increase the level of testosterone and nitric oxide. It can be inferred that both plants could be promising natural therapy for erectile dysfunction. Nonetheless, the plants’ extracts are toxic hence should be taken with caution.
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