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Prof 

Zharare, Godfrey Elijah

Department: Agriculture
Research Interest(s): Extraction and Physiochemical properties of essential and Vegetable oils, Botany and genetics of oil-bearing plants, Cosmeceutical, pharmaceatical utilization od esseantial, and vegetable oils.
Active Research Project(s): Bio-refinery of Strychnos madagascariensis fruit (Ikwakwa). Validation of Ikwaflakes and Kwafee as nutraceutical foods for managing Hyperlipidaemia, Diabetes, and Hypertension. Optimization of Oil Extraction from Strychnos madagascariensis and Technology Transfer. Variation in morphology, Proximate components, and Genetic attributes of Strychic spinosa genotypes. Morphological variation, Genetics, Volatile oil yield in Laggera alata, and Laggera crispata species in Northern KwaZulu-Natal, South Africa.
Active Community Engagement: UNIZULU King Cetshwayo District Content Workshop for grade 10-12 economics educators (2021).
Biography: Prof G.E. Zharare is Professor under Agriculture Department in the Faculty of Science, Agriculture and Engineering at the University of Zululand. He is Plant Scientist with specialization in Agronomy and plant physiology. Prof Zharare is an NRF C3 rated researcher who has published numerous peer-reviewed articles. He has supervised many postgraduate students to completion in plant sciences. He also acts as a reviewer for a number of international journals on plant sciences.

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  • PublicationJournal Article
    Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the in vitro and in vivo antioxidant potential of the methanolic extracts of Inula glomerata and Salacia kraussii. The plant materials were pulverized and extracted with methanol. The phytochemical analysis, ability of the crude extracts to scavenge free radicals (ABTS, DPPH, NO.) in vitro as well as the total phenolic and flavonoid contents was investigated. In vivo, antioxidant potentials of the crude extracts (50/250 mg/kg body weight) were determined in an erectile dysfunction rat model. The phytochemical analysis revealed that both plants contain flavonoids, tannins, terpenoids, and alkaloids. The crude extracts at varying degree of efficiency, scavenged ABTS and DPPH radicals. The crude extracts at low concentrations (50 mg/kg bw) significantly (p< 0.05) diminished the level of malondialdehyde, augmented catalase activities and elevated glutathione levels. However, SOD activities were significantly boosted in a dose-dependent manner by the crude extracts. Therefore, I. glomerata and S. kraussii possess antioxidant properties, hence, can serve as a therapeutic modality in the treatment of oxidative stress-induced erectile dysfunction.
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